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McKesson · EDI 855

The McKesson 855 Purchase Order Acknowledgment, explained

What McKesson expects in the 855 — confirms what you can ship against the PO — quantities, dates, substitutions — and how EDISQ's certified map handles it from your ERP.

Connect to McKesson free 855 glossary guide

What McKesson expects in the 855

McKesson trades on X12 4010 over VAN. Beyond the base standard, watch these:

ACK codesline-level IA/IB/IR status expected on every line — accept, backorder, reject
Backorderbackordered lines carry a revised availability date; an open-ended hold reads as a cancel
Timingacknowledge same day — pharmaceutical replenishment cycles are measured in hours, not days

How EDISQ maps it

The certified McKesson 855 map loads when you enable the partner — fields auto-map from NetSuite, QuickBooks, Dynamics, and 33 other systems, validation runs against McKesson's spec before transmission, and the sandbox replays McKesson test scenarios until everything passes.

Common rejection reasons

Nearly all 855 rejections trace to reference data, not syntax: identifiers that don't match McKesson's cross-references, echoed fields dropped from the original PO, or timing that misses the program window. EDISQ flags each before McKesson ever sees the document.

Sample McKesson 855

A representative 855 interchange addressed to McKesson — envelope, body segments, and control totals:

1ISA*00*          *00*          *ZZ*ACMESUPPLY     *ZZ*MCKESSON       *260101*1200*U*00401*000000001*0*P*>~
2GS*PR*ACMESUPPLY*MCKESSON*20260101*1200*1*X*004010~
3ST*855*0001~
4BAK*00*AC*PO12345*20260101~
5PO1*1*24*EA*9.75**UP*012345678905~
6ACK*IA*24*EA~
7PO1*2*12*EA*14.50**UP*012345678912~
8ACK*IA*12*EA~
9CTT*2~
10SE*8*0001~
11GE*1*1~
12IEA*1*000000001~

FAQ

Which 855 version does McKesson use?

X12 4010, delivered over VAN. The certified map tracks McKesson's current companion guide.

How do I test a McKesson 855?

The sandbox generates realistic McKesson 855 scenarios against your live mapping — free, unlimited, invisible to McKesson.

What does it cost?

Per document only: first 25/month free, then from $0.50, decreasing with volume. No partner or mapping fees.