McKesson · EDI 850

The McKesson 850 Purchase Order, explained

What McKesson expects in the 850 — the order a trading partner sends you. Process same day, never re-key — and how EDISQ's certified map handles it from your ERP.

Connect to McKesson free 850 glossary guide

What McKesson expects in the 850

McKesson trades on X12 4010 over VAN. Beyond the base standard, watch these:

N1*STorders route across a national pharmaceutical DC network — keep the location cross-reference current
PO1NDC and McKesson item number both appear on the line; map in both directions

How EDISQ maps it

The certified McKesson 850 map loads when you enable the partner — fields auto-map from NetSuite, QuickBooks, Dynamics, and 33 other systems, validation runs against McKesson's spec before transmission, and the sandbox replays McKesson test scenarios until everything passes.

Common rejection reasons

Nearly all 850 rejections trace to reference data, not syntax: identifiers that don't match McKesson's cross-references, echoed fields dropped from the original PO, or timing that misses the program window. EDISQ flags each before McKesson ever sees the document.

Sample McKesson 850

A representative 850 interchange addressed to McKesson — envelope, body segments, and control totals:

1ISA*00*          *00*          *ZZ*ACMESUPPLY     *ZZ*MCKESSON       *260101*1200*U*00401*000000001*0*P*>~
2GS*PO*ACMESUPPLY*MCKESSON*20260101*1200*1*X*004010~
3ST*850*0001~
4BEG*00*SA*PO12345**20260101~
5REF*DP*056~
6DTM*002*20260110~
7N1*ST*MCKESSON DC 5093*92*5093~
8PO1*1*24*EA*9.75**UP*012345678905~
9PID*F****ACME WIDGET 24CT~
10PO1*2*12*EA*14.50**UP*012345678912~
11PID*F****ACME GADGET 12CT~
12CTT*2~
13SE*11*0001~
14GE*1*1~
15IEA*1*000000001~

FAQ

Which 850 version does McKesson use?

X12 4010, delivered over VAN. The certified map tracks McKesson's current companion guide.

How do I test a McKesson 850?

The sandbox generates realistic McKesson 850 scenarios against your live mapping — free, unlimited, invisible to McKesson.

What does it cost?

Per document only: first 25/month free, then from $0.50, decreasing with volume. No partner or mapping fees.