CVS Pharmacy EDI: Requirements, Setup & Compliance

What CVS Pharmacy requires

850

Purchase Order

The order a trading partner sends you. Process same day, never re-key.

855

Purchase Order Acknowledgment

Confirms what you can ship against the PO — quantities, dates, substitutions.

856

Ship Notice / ASN

The carton-level shipment mirror that must arrive before the freight does.

810

Invoice

Your bill for the shipment. Must reconcile with the PO and the ASN.

997

Functional Acknowledgment

The receipt for every document. Automatic, both directions, within minutes.

Compliance matters here: CVS supplier compliance (ASN + appointment deductions). EDISQ validates every outbound document against CVS Pharmacy's companion guide before transmission, so chargebacks stop at the map.

How EDISQ connects to CVS Pharmacy

CVS Pharmacy trades AS2 direct. EDISQ maintains the AS2 connection and certificates, registers your IDs, and loads the certified maps the moment you enable the partner:

1Enable CVS Pharmacy from the partner catalog — document maps load automatically.

2Cross-reference your data — vendor number, ship-to locations, item identifiers. The wizard flags anything missing.

3Run test scenarios in the sandbox — validated end-to-end before anything goes live.

Typical CVS Pharmacy setup with EDISQ: 2–3 days on the EDI side.

Pricing for CVS Pharmacy suppliers

No CVS Pharmacy-specific fees. First 25 documents/month free, then $0.50 per document, cheaper as volume grows — no VAN, mapping, or partner fees. Full pricing →

CVS Pharmacy EDI FAQ

Does CVS trade direct or through a network?

AS2 direct. EDISQ maintains the connection and certificates — included in the per-document price.

What does EDI with CVS cost?

Per document only: first 25/month free, then from $0.50, decreasing with volume.

EDI with CVS Pharmacy, without the monthly fee